In this blog for patients and doctors, Dr Mark Horowitz, training psychiatrist and Clinical Research Fellow at University College London, looks at the latest Cochrane evidence on how to safely stop antidepressants and explores the implications for patients and doctors having to navigate this area so neglected by medical researchers. Mark’s personal experience of the difficulty in coming off antidepressants led to an interest in the little-understood field of stopping psychiatric medication, and the balance of harms and benefits.