The latest evidence and resources for nurses and clinical support staff. You can either scroll through this page or click on any of the links below to jump to the relevant section.
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- Care of the newborn, including preterm infants
- Chronic kidney disease
- Critical and emergency care
- Diet for prevention of cardiovascular disease
- End-of-life care
- Healthcare worker education and training
- Healthy ageing
- Heparin injections: slow versus fast delivery
- Hypertension and overweight or obesity
- Living with long-term conditions
- Mental health
- Post-operative care
- Pressure ulcers
- Probiotics for acute infectious diarrhoea
- Pulmonary embolism
- Soft tissue injury (acute)
- Smoking cessation
- Vitamin D supplementation for children
- Opportunities to get involved with Cochrane
This year, Cochrane is continuing to produce new and updated reviews in response to the pandemic. We have blogged about many of them and this blog COVID-19 evidence: a Cochrane round-up brings together a large collection of evidence and resources, starting from when this evidence was first being produced in spring 2020. Like the reviews themselves, all our blogs are updated to reflect new evidence.
A Cochrane Review COVID‐19 and its cardiovascular effects: a systematic review of prevalence studies (March 2021) has looked at both cardiovascular problems pre-existing the development of COVID-19 and assesses the risk of cardiovascular complications, highlighting which are the most common (unexpectedly, this was atrial fibrillation). Senior author Professsor John GF Cleland discusses it in this interview. He comments that “These results show what the clinical teams looking after patients with COVID should watch out for. Clinical teams are already aware of the risk of blood clots but may be less aware of the risk of developing atrial fibrillation or heart failure. Also, heart failure may be difficult to diagnose in a patient with COVID, so great care and attention is required not to miss this treatable diagnosis.” There is a Cochrane Clinical Answer and a Cochrane Podcast for this review.
In our blog Convalescent plasma to treat people with COVID-19: the evidence so far (updated May 2021) you can catch up with the latest evidence from the most recent update of the Cochrane Review.
Cochrane’s response to the pandemic had to meet the needs of evidence users and decision‐makers as it developed and how this is being done is discussed in an Editorial COVID-19: working together and making a difference for decision-makers. Cochrane has also signed on to the World Health Organization’s call for action about managing infodemics and WHO’s Vaccine Equity Declaration.
External to Cochrane, you might be interested to read about this work being done on the Impact of COVID-19 and other conditions requiring isolation on the provision of fundamental nursing care in hospital.
Cochrane Special Collections
Cochrane Special Collections assemble You can find Coronavirus (COVID-19) Special Collections here. Among them is the Special Collection Physical activity for healthy ageing which was updated in April 2021, of COVID-19. They are developed with experts from our global Cochrane network. They are based on World Health Organization interim guidance, and continuously updated. on important topics for the prevention and Coronavirus (COVID-19): evidence relevant to critical care updated in June 2021, and Coronavirus (COVID-19): optimizing health in the home workspace, updated in June 2021.
Cochrane COVID-19 Podcasts offer short summaries of Cochrane COVID-19 reviews from the authors themselves. A good way to hear the latest in under 5 minutes each.
Cochrane Clinical Answers
Cochrane Clinical Answers (CCAs) provide a readable, digestible, clinically-focused entry point to rigorous research from Cochrane Reviews. They are designed to be actionable and to inform point-of-care decision-making.
Each CCA contains a clinical question, a short answer, and from the Cochrane Review deemed most relevant to practising healthcare professionals. for the
The evidence is displayed in a user-friendly tabulated format that includes narratives, data, and links to graphics.
Inhaled corticosteroids for chronic asthma
Cochrane Review: Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an inhaled corticosteroid for chronic asthma: serious adverse events (April 2021)
Cochrane Clinical Answers (both derived from the above review):
Inhalers for mild asthma
Cochrane Clinical Answer: Can weight loss interventions improve outcomes for overweight and obese breast cancer survivors?
Care of the newborn, including preterm infants
Antibiotics for early-onset neonatal sepsis
Cochrane Review: Antibiotic regimens for early‐onset neonatal sepsis (May 2021)
Ibuprofen for preventing patent ductus arteriosus
Feeding preterm infants
Cochrane Review: Continuous nasogastric milk feeding versus intermittent bolus milk feeding for preterm infants less than 1500 grams (June 2021)
Management of transient tachypnoea of the newborn
For this recent Cochrane Review: Fluid restriction in the management of transient tachypnea of the newborn (February 2021) there is now a Cochrane Clinical Answer: How does restricted fluid management compare with standard fluid management for preventing transient tachypnea in neonates?
Opioids for ventilated newborns
Cochrane Review: Oral dextrose gel to prevent hypoglycaemia in at‐risk neonates (May 2021)
Cochrane Clinical Answer: What are the effects of oral dextrose for preventing hypoglycemia in at‐risk neonates?
Sedatives for opioid withdrawal in newborns
Cochrane Review: Sedatives for opioid withdrawal in newborn infants (May 2021)
Cochrane Clinical Answer: For newborn infants with opiate withdrawal, how do different sedatives compare?
Cochrane Review: Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome (May 2021)
Topical emollient for preventing infection
Cochrane Review: Topical emollient for preventing infection in preterm infants (May 2021)
Cochrane Clinical Answer: How do topical emollients compare with routine skin care for preventing infection in preterm infants?
Chronic kidney disease
For the Cochrane Review Urgent‐start peritoneal dialysis versus haemodialysis for people with chronic kidney disease (January 2021) there is now a Cochrane Clinical Answer: How does urgent‐start peritoneal dialysis compare with urgent‐start central venous catheter hemodialysis for adults with chronic kidney disease?
Critical and emergency care
Critical care telemedicine
High-flow nasal cannulae
Cochrane Review: High‐flow nasal cannulae for respiratory support in adult intensive care patients (March 2021)
Cochrane Clinical Answer: For adults in intensive care requiring respiratory support, how does a high‐flow nasal cannula compare with standard oxygen therapy and non‐invasive (positive‐pressure) ventilation (NI[PP]V)?
PEEP levels for mechanically ventilated adults
Stopping or continuing anti-dementia drugs
See also the section on ‘living with long-term conditions’.
Diabetes and pregnancy
An Evidently Cochrane blog by Emma Doble, who has Type 1 diabetes – Balancing diabetes and pregnancy: the keys are shared decision-making and technology.
You might also be interested in this blog on Contemplating pregnancy with long-term health conditions.
Type 1 diabetes and long-acting analogs
Cochrane Clinical Answers:
Diet for prevention of cardiovascular disease
Hospital at home
Cochrane Review: Hospital at home: home‐based end‐of‐life care (March 2021)
Cochrane Clinical Answer:
Hospital-based specialist palliative care
Cochrane Clinical Answer: How does hospital‐based specialist palliative care (HSPC) affect adults with advanced illness?
Healthcare worker education and training
Cochrane in partnership: The United Nations (UN) Decade of Healthy Ageing. Our next special series (autumn 2021) will be on Healthy Ageing.
Heparin injections: slow versus fast delivery
Cochrane Review: Slow versus fast subcutaneous heparin injections for prevention of bruising and site pain intensity (June 2021)
Hypertension and overweight or obesity
Cochrane Review: Long‐term effects of weight‐reducing diets in people with hypertension (February 2021)
Cochrane Clinical Answer: For people with hypertension and overweight or obesity, what are the effects of weight‐reducing diets?
Living with long-term conditions
Living with long-term conditions: a Cochrane UK special series has multiple blogs, offering perspectives from patients, health professionals and researchers. You can read all the blogs in this series here. Some are listed elsewhere on this page by topic (eg. mental health, diabetes). Our Consumer Champions have shared their experiences in Living with a long-term condition: five perspectives – part 1 and Living with a long-term condition: five perspectives – part 2. There is a blog on research to improve pregnancy outcomes for women with long-term conditions – Contemplating pregnancy with long-term health conditions. There’s a blog on a new trial comparing hearing aids with cochlear implants: Severe hearing loss in adults: finding out whether cochlear implants or hearing aids are better and a blog on biologics for treating arthritis: are they the greatest advance this century?
There is a blog on The impact of language on people living with long-term conditions and a tweetchat on this topic is summarised in this blog Language matters: the use and misuse of language when talking about long-term conditions.
New generation antidepressants
Interventions for self-harm
Pharmacological interventions for self‐harm in adults (January 2021)
Psychosocial interventions for self‐harm in adults (April 2021)
Organisation of care
Myra Robson, a pelvic health physiotherapist, has written an Evidently Cochrane blog Pessaries for pelvic organ prolapse – looking at the Cochrane evidence.
NICE seek comments on draft guidance on pelvic floor dysfunction
NICE has recently published draft guidance on pelvic floor dysfunction and the importance of exercises and has opened a period of consultation from stakeholders, until 9 August 2021.
A suite of five Cochrane Reviews has been published on different support surfaces to prevent or treat pressure ulcers. An overview of reviews, with network meta-analysis, is being prepared, which will bring this evidence together. We anticipate having an Evidently Cochrane blog on this when it is published, in the next few months.
The reviews, all published in May 2021, are: Reactive air surfaces for preventing pressure ulcers, Foam surfaces for preventing pressure ulcers, Alternative reactive support surfaces (non‐foam and non‐air‐filled) for preventing pressure ulcers, Alternating pressure (active) air surfaces for preventing pressure ulcers, and Beds, overlays and mattresses for treating pressure ulcers.
There is also recent Cochrane Review on Patient and lay carer education for preventing pressure ulceration in at‐risk populations (February 2021) and a related Cochrane Clinical Answer: For people at risk of developing pressure ulcers, what are the effects of patient and lay carer pressure ulcer education and prevention care bundles?
Probiotics for acute infectious diarrhoea
Cochrane Review: Thrombolytic therapy for pulmonary embolism (April 2021)
Soft tissue injury (acute)
Cochrane Special Collections:
Stopping tobacco use (May 2021)
Cochrane Clinical Answer: How effective and safe are electronic cigarettes (ECs) for smoking cessation?
Cochrane Clinical Answer: How do oral health interventions compare with usual care for improving outcomes in people after stroke?
Vitamin D supplementation for children
For the Cochrane Review Effects of oral vitamin D supplementation on linear growth and other health outcomes among children under five years of age (December 2020) there is now a Cochrane Clinical Answer For infants and children younger than 5 years of age, what are the effects of vitamin D supplementation on linear growth and other health outcomes?
Opportunities to get involved with Cochrane
On this page, Important Cochrane Links, you can find opportunities to get involved, including how to join Cochrane, find volunteer tasks, or jump into the Cochrane Library.
Find out more about Cochrane’s Early Career Professionals Group and their upcoming activities.
Please note that this page includes a round-up of materials mainly published within the last three months, and is not updated after it’s posted.
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